EXPRESSION OF LIPID-METABOLISM GENES IS CORRELATED WITH IMMUNE MICROENVIRONMENT AND PREDICTS PROGNOSIS IN OSTEOSARCOMA

Expression of Lipid-Metabolism Genes Is Correlated With Immune Microenvironment and Predicts Prognosis in Osteosarcoma

ObjectivesOsteosarcoma was the most popular primary malignant tumor in children and adolescent, and the 5-year survival of osteosarcoma patients gained no substantial improvement over the past 35 years.This read more study aims to explore the role of lipid metabolism in the development and diagnosis of osteosarcoma.MethodsClinical information and c

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Capacitated Refuge Assignment for Speedy and Reliable Evacuation

When a large-scale disaster occurs, each evacuee should move to an appropriate refuge in a speedy and safe manner.Most of the existing studies on the refuge assignment consider the speediness of evacuation and refuge capacity while the safety click here of evacuation is not taken into account.In this paper, we propose a refuge assignment scheme tha

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The evolution of microstructure and texture of AZ80 and AZ80-LaMM magnesium alloy wheel hubs processed by single-pass radial forging

In this paper, 1.5 wt% La-rich Mish Metal (LaMM) was added to AZ80 magnesium alloy, and microstructure evolution, texture development of AZ80 wheel hub were studied by single-pass radial forging, so as to provide basic data for the preparation of magnesium alloy wheel hub with uniform microstructure and excellent mechanical properties.A detailed mi

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Taurine depletion during fetal and postnatal development blunts firing responses of neocortical layer II/III pyramidal neurons

Fetal and infant brains are rich in maternally derived taurine.We previously demonstrated that taurine action regulates the cation-chloride cotransporter activity and the differentiation and radial migration of pyramidal neuron progenitors in the developing neocortex of rodent fetuses.Here we examined the effects of fetal and infantile taurine depl

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